I have no idea why people are naming things like Dragon Ball Z or Pokemon, because in my opinion those are the two animes that made anime popular in the U.S. in the first place.
For me I'm going to have to say Digimon, I used to wach it I loved it whatever, then they changed all the main characters it's like ok.
BoBoBo-bo-bo-bobo looks so random I don't even bother with it.
I wish I had never seen FLCL, it was so weird and very short so eh.
As of Pokemon they need to relax, they have to be at like episode 800, there is no way someone could see it all they've been playing it for so many years.